Watching proteins in motion
نویسندگان
چکیده
منابع مشابه
Watching single proteins using engineered nanopores.
Recent studies in the area of single-molecule detection of proteins with nanopores show a great promise in fundamental science, bionanotechnology and proteomics. In this mini-review, I discuss a comprehensive array of examinations of protein detection and characterization using protein and solid-state nanopores. These investigations demonstrate the power of the single-molecule nanopore measurem...
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In traditional biochemical experiments, the behavior of individual proteins is obscured by ensemble averaging. To better understand the behavior of proteins that bind to and/or translocate on DNA, we have developed instrumentation that uses optical trapping, microfluidic solution delivery, and fluorescent microscopy to visualize either individual proteins or assemblies of proteins acting on sin...
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encoding proteases within any genome are easily identified, and three-dimensional structures of many proteases have been solved. Most proteolytic cleavage mechanisms and pro-tease substrate specificities have been established (the latter in some detail) 1. We are also able to block proteolytic activities with potent inhibi-tors. Transgenic approaches have been used for targeted deletions of pro...
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Fictive Motion is a type of figurative language used to express static visual scenes in terms of motion, for example, ”The road runs along the river” or ”The scar runs down his back”. Previous research suggests that we mentally simulate fictive motion (Matlock 2004, Matlock & Bergmann, in press), but little is known about the use of fictive motion in real discourse. Our study is the first to lo...
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Several things, that were not all of my own choosing, have conspired to keep me out of active participation in membrane events for a while. But the spectator sport that I call "membrane watching" is far from dull. It may be as rewarding as such things as birds, Congress, girls, bali games, or the Berkeley campus-particularly when you feel yourself somewhat qualified. Of course you lose the trem...
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ژورنال
عنوان ژورنال: Genome Biology
سال: 2009
ISSN: 1465-6906
DOI: 10.1186/gb-2009-10-10-316